AGR2+AGR3 anticorps
Reactivité: Humain
WB, ICC, IHC (p)
Hôte: Souris
Monoclonal
AGR3-4
unconjugated
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- Antigène Tous les produits AGR2+AGR3
- AGR2+AGR3
- Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp AGR2+AGR3 est non-conjugé
- Application
- Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- The antibody AGR3.4 recognizes the PLMII epitope of AGR3 (AG3) and AGR2 (AG2) proteins (19-20 kDa), secreted cytoplasmic proteins which can serve as markers of carcinogenesis.
- Réactivité croisée (Details)
- Human, Other species Not tested
- Purification
- Purified by protein-A affinity chromatography.
- Pureté
- > 95 % (by SDS-PAGE)
- Immunogène
- Purified human AGR3 protein
- Clone
- AGR3-4
- Isotype
- IgG1
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- Indications d'application
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Immunohistochemistry (paraffin sections): Recommended dilution: 5 μg/mL, Positive tissue: human colon.
Western blotting: Recommended dilution: 1 μg/mL, positive control: T47D breast cancer cell line, negative control: H1299 lung carcinoma cell line.
Immunocytochemistry: Recommended dilution: 1 μg/mL, positive control: T47D breast cancer cell line, negative control: H1299 lung carcinoma cell line. - Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Do not freeze.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Do not freeze.
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- Antigène
- AGR2+AGR3
- Abstract
- AGR2+AGR3 Produits
- Synonymes
- anticorps AG3, anticorps BCMP11, anticorps HAG3, anticorps PDIA18, anticorps hAG-3, anticorps E030025L21Rik, anticorps Gm888, anticorps anterior gradient 3, protein disulphide isomerase family member, anticorps anterior gradient 3, anticorps AGR3, anticorps Agr3
- Sujet
- AGR2 (Anterior Gradient 2), also known as AG2 (hAG-2, HAG2 in human), or GOB-4, and AGR3 (Anterior Gradient 3), also known as AG3 (hAG-3, HAG3 in human), or BCMP11, are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours, AGR2 was reported also as a marker of other carcinomas. Xenopus homolog of these proteins is associated with anteroposterior fate determination during early development.,AG2, AG3, HAG2, HAG3
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