DPYSL3 anticorps (C-Term)

N° du produit ABIN347041

Cet anticorps Lapin Polyclonal détecte spécifiquement DPYSL3 dans WB, ELISA et IHC. Il présente une réactivité envers Humain et a été mentionné dans 5+ publications.

Aperçu rapide pour DPYSL3 anticorps (C-Term) (ABIN347041)

Antigène: DPYSL3 (Dihydropyrimidinase-Like 3 (DPYSL3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DPYSL3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-DPYSL3 anticorps

Épitope: C-Term

Specificité: Reacts with 65 kDa CRMP-4 from human rat and mouse

Réactivité croisée (Details): Do not react with CRMP-1, CRMP-2, CRMP-3 or CRMP-5.

Purification: Antiserum

Immunogène: A 15 residue synthetic peptide derived from C-terminal domain of human collapsing-response mediator

Isotype: IgG

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
-IHC : 1/500 - WB :1/2 000

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Stock: 4 °C/-20 °C

Stockage commentaire: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Date de péremption: 24 months

Références pour anticorps anti-DPYSL3 (ABIN347041)

Blasco, Bernard-Marissal, Vourch, Guettard, Sunyach, Augereau, Khederchah, Mouzat, Antar, Gordon, Veyrat-Durebex, Besson, Andersen, Salachas, Meininger, Camu, Pettmann, Andres, Corcia: "A rare motor neuron deleterious missense mutation in the DPYSL3 (CRMP4) gene is associated with ALS." dans: Human mutation, Vol. 34, Issue 7, pp. 953-60, (2013) (PubMed).

Bretin, Reibel, Charrier, Maus-Moatti, Auvergnon, Thevenoux, Glowinski, Rogemond, Prémont, Honnorat, Gauchy: "Differential expression of CRMP1, CRMP2A, CRMP2B, and CRMP5 in axons or dendrites of distinct neurons in the mouse brain." dans: The Journal of comparative neurology, Vol. 486, Issue 1, pp. 1-17, (2005) (PubMed).

Ricard, Rogemond, Charrier, Aguera, Bagnard, Belin, Thomasset, Honnorat: "Isolation and expression pattern of human Unc-33-like phosphoprotein 6/collapsin response mediator protein 5 (Ulip6/CRMP5): coexistence with Ulip2/CRMP2 in Sema3a- sensitive oligodendrocytes." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 21, Issue 18, pp. 7203-14, (2001) (PubMed).

Honnorat, Byk, Kusters, Aguera, Ricard, Rogemond, Quach, Aunis, Sobel, Mattei, Kolattukudy, Belin, Antoine: "Ulip/CRMP proteins are recognized by autoantibodies in paraneoplastic neurological syndromes." dans: The European journal of neuroscience, Vol. 11, Issue 12, pp. 4226-32, (2000) (PubMed).

Balin, Loewy, Appelt: "Analysis of transglutaminase-catalyzed isopeptide bonds in paired helical filaments and neurofibrillary tangles from Alzheimer's disease." dans: Methods in enzymology, Vol. 309, pp. 172-86, (1999) (PubMed).

Détails sur DPYSL3

Antigène: DPYSL3 (Dihydropyrimidinase-Like 3 (DPYSL3))

Autre désignation: Collapsin Response Mediator Protein 4 (CRMP-4)

Sujet: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration

UniProt: Q14195