PLCz1 anticorps (Internal Region)

N° du produit ABIN347397

Cet anticorps Lapin Polyclonal détecte spécifiquement PLCz1 dans ELISA, WB, IHC et ICC. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour PLCz1 anticorps (Internal Region) (ABIN347397)

Antigène: PLCz1 (Phospholipase C zeta 1 (PLCz1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLCz1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Détail du produit anti-PLCz1 anticorps

Épitope: Internal Region

Specificité: Reacts with human PLC zeta protein

Réactivité croisée (Details): No cross reaction

Purification: Antiserum

Immunogène: Synthetic peptide derived from internal part of PLC-zeta-1

Isotype: IgG

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB(1:100 - 1:1000) ICC(1:50 - 1:1000)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Stock: 4 °C/-20 °C

Stockage commentaire: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Date de péremption: 24 months

Références pour anticorps anti-PLCz1 (ABIN347397)

Janghorban-Laricheh, Ghazavi-Khorasgani, Tavalaee, Zohrabi, Abbasi, Nasr-Esfahani: "An association between sperm PLCζ levels and varicocele?" dans: Journal of assisted reproduction and genetics, (2016) (PubMed).

Kamali-Dolat Abadi, Tavalaee, Shahverdi, Nasr-Esfahani: "Evaluation of PLCζ and PAWP Expression in Globozoospermic Individuals." dans: Cell journal, Vol. 18, Issue 3, pp. 438-45, (2016) (PubMed).

Détails sur PLCz1

Antigène: PLCz1 (Phospholipase C zeta 1 (PLCz1))

Autre désignation: Phospholipase C zeta Isoform (PLC-zeta-1)

Sujet: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca2+-dependent manner. Triggers intracellular Ca2+ oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion.

ID gène: 89869

UniProt: Q86YW0