FAP anticorps (Internal Region)

N° du produit ABIN349584

N° du produit (Fournisseur): 600-401-a73

L’anticorps Lapin Polyclonal anti-FAP a été validé pour WB et ELISA. Il convient pour détecter FAP dans des échantillons de Souris.

Aperçu rapide pour FAP anticorps (Internal Region) (ABIN349584)

Antigène: FAP (Fibroblast Activation Protein, alpha (FAP))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAP est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-FAP anticorps

Épitope: Internal Region

N° du produit (Fournisseur): 600-401-a73

Fournisseur: Rockland

Fonction: Fibroblast Activation Protein Antibody

Réactivité croisée (Details): This antibody is known to react with mouse FAP protein.

Attributs du produit: Synonyms: rabbit anti-Fap antibody, Fibroblast activation protein alpha, Prolyl endopeptidase FAP, Dipeptidyl peptidase FAP, Integral membrane serine protease antibody, FAPA antibody, Gelatine degradation protease FAP, Surface-expressed protease, SIMP, Seprase, APCE

Purification: This product was affinity purified from monospecific antiserum by immunoaffinity chromatography.

Stérilité: Sterile filtered

Immunogène:

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of mouse FAP protein.

Immunogen Type: Conjugated Peptide

Isotype: IgG

Information d'application

Indications d'application:

Application Note: This affinity purified antibody has been tested for use in ELISA and western blotting.  Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 88 kDa in size corresponding to FAP by western blotting in the appropriate cell lysate or extract.

Western Blot Dilution: 1:500 to 1:2,000

ELISA Dilution: 1:10,000 - 1:20,000

Other: User Optimized

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.81 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur FAP

Antigène: FAP (Fibroblast Activation Protein, alpha (FAP))

Autre désignation: Fap

Sujet: Background: This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. Fibroblast Activation Protein (FAP)  is expressed in the stroma of sites that are undergoing wound healing. In addition, it has recently been reported that FAP is expressed in the stroma of sites of metastatic disease. Inhibition of FAP may lead to a dramatic decrease in the number of metastatic osteosarcoma lung nodules.  FAP exists as an inactive monomer and when activated forms homodimers or heterodimers with DPP4.  Multiple isoforms of FAP are reported as alternative splicing products from a common gene.

ID gène: 14089, 6679749

UniProt: P97321

Pathways: Tube Formation