Arc anticorps
Aperçu rapide pour Arc anticorps (ABIN350080)
Antigène
Voir toutes Arc AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Sheep antibody to Arg3.1
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Specificité
- Specific for Arg3.1/ARC.
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Réactivité croisée
- Humain, Souris, Rat
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Réactivité croisée (Details)
- Other species not yet tested.
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Purification
- IgG
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Immunogène
- A synthetic peptide from human Arg3.1 (ARC) conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
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Isotype
- IgG
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Indications d'application
- IHC WB (confirmed by recombinant protein). Use at a concentration of 10-50 μg,ml. The optimal working concentration should be determined by the end user. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
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Conseil sur la manipulation
- Avoid freeze and thaw cycles.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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Date de péremption
- 12 months
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- Arc (Activity-Regulated Cytoskeleton-Associated Protein (Arc))
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Autre désignation
- Arg3.1
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Sujet
- FUNCTION: Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors. SUBCELLULAR LOCATION: Cytoplasm cytoskeleton. Endosome. Acrosome. Cell junction synapse postsynaptic cell membrane postsynaptic density. Cell projection dendrite. Cell projection dendritic spine. Cell junction synapse. Note=Associated with the cell cortex of neuronal soma and dendrites. Enriched in postsynaptic density of dendritic spines. Associated with the sperm tail.
Antigène
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