Pro-Hepcidin (AA 39-59) anticorps

N° du produit ABIN350367

Cet anticorps anti- est un anticorps Lapin Polyclonal détectant dans IHC et WB. Adapté pour Souris. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour Pro-Hepcidin (AA 39-59) anticorps (ABIN350367)

Antigène: Pro-Hepcidin

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Détail du produit

Épitope: AA 39-59

Fonction: Rabbit antibody to pro Hepcidin (39-59)

Specificité: Specific for Hepcidin.

Réactivité croisée: Souris

Réactivité croisée (Details): Other species not yet tested.

Purification: IgG

Immunogène: A synthetic peptide from AA 39-59 of pro region of mouse Hepcidin conjugated to blue carrier protein has been used as the antigen.

Isotype: IgG

Information d'application

Indications d'application: IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Référence

Mohammad, Matakidou, Robbins, Lakhal-Littleton: "The kidney hepcidin/ferroportin axis controls iron reabsorption and determines the magnitude of kidney and systemic iron overload." dans: Kidney international, Vol. 100, Issue 3, pp. 559-569, (2021) (PubMed).

Détail du antigène

Antigène: Pro-Hepcidin

Autre désignation: pro Hepcidin

Sujet: FUNCTION: Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages. May also have antimicrobial activity. SUBCELLULAR LOCATION: Secreted. Tissue specificity: Highly expressed in the liver and to a much lesser extent in the heart.

UniProt: Q9EQ21