Huntingtin anticorps (AA 1150-1200)

N° du produit ABIN350377

Cet anticorps Lapin Polyclonal détecte spécifiquement Huntingtin dans IHC et WB. Il présente une réactivité envers Rat.

Aperçu rapide pour Huntingtin anticorps (AA 1150-1200) (ABIN350377)

Antigène: Huntingtin (HTT)

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Huntingtin est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Détail du produit anti-Huntingtin anticorps

Épitope: AA 1150-1200

Fonction: Rabbit antibody to Huntingtin

Specificité: Specific for Huntingtin.

Réactivité croisée: Souris, Rat

Réactivité croisée (Details): Other species not yet tested.

Purification: IgG

Immunogène: A synthetic peptide from AA 1150-1200 of rat Huntingtin conjugated to blue carrier protein was used as the antigen. The peptide shares 87% identity with mouse and human sequences.

Isotype: IgG

Information d'application

Indications d'application: IHC WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Détails sur Huntingtin

Antigène: Huntingtin (HTT)

Autre désignation: Huntingtin

Sujet: FUNCTION: May play a role in microtubule-mediated transport or vesicle function. SUBCELLULAR LOCATION: Cytoplasm. Nucleus. TISSUE SPECIFICITY: Expressed to a high degree in all the regions of the brain of adults and in meiotic cells of the testis. In addition very low levels are detected in various non-neuronal tissues (heart muscle liver lung and kidney). DEVELOPMENTAL STAGE: Identified at high levels in neuronal tissues of embryos as early as day 14.5. This expression remains constant in all further development stages (up to the adult). On the other hand the expression in non-neuronal tissues is down-regulated from stage 17.5 day old embryos.

UniProt: P51111

Pathways: Signalisation PI3K-Akt, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport