LIMK2 anticorps (pSer291, pSer293)

N° du produit ABIN350730

Cet anticorps anti-LIMK2 est un anticorps Lapin Polyclonal détectant LIMK2 dans WB et IHC. Adapté pour Humain.

Aperçu rapide pour LIMK2 anticorps (pSer291, pSer293) (ABIN350730)

Antigène: LIMK2 (LIM Domain Kinase 2 (LIMK2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIMK2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-LIMK2 anticorps

Épitope: pSer291, pSer293

Fonction: Rabbit antibody to phospho S291 & S293 LIMK2

Specificité: Specific for LIMK2.

Réactivité croisée: Humain, Souris, Rat

Réactivité croisée (Details): Other species not yet tested.

Purification: IgG

Immunogène: A synthetic peptide from the phospho S291 & S293 region of human LIMK2 (LIM domain kinase 2 LIMK-2) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat mouse.

Isotype: IgG

Information d'application

Indications d'application: IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. This antibody may also recognise the unphosphorylated form. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Détails sur LIMK2

Antigène: LIMK2 (LIM Domain Kinase 2 (LIMK2))

Autre désignation: LIMK2

Sujet: FUNCTION: Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro. CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein. SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note: Isoform LIMK2a is distributed in the cytoplasm and the nucleus and isoform LIMK2b occurs mainly in the cytoplasm and is scarcely translocated to the nucleus. TISSUE SPECIFICITY: Highest expression in the placenta, moderate level in liver lung kidney and pancreas. LIMK2a is found to be more abundant then LIMK2b in liver colon stomach and spleen while in brain kidney and placenta LIMK2b is the dominant form. In adult lung both LIMK2a and LIMK2b is nearly equally observed.

UniProt: P53671