A synthetic peptide from the c-terminal region of human Pr3 (Leukocyte proteinase 3 AGP7 Myeloblastin Wegener autoantigen) conjugated to blue carrier protein was used as the antigen.
WB IHC flow cytometry. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Conseil sur la manipulation
Avoid freeze and thaw cycles.
Stock
4 °C,-20 °C
Stockage commentaire
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Date de péremption
12 months
Antigène
PRTN3
(Proteinase 3 (PRTN3))
Autre désignation
Pr3
Sujet
FUNCTION: Polymorphonuclear leukocyte serine protease that degrades elastin fibronectin laminin vitronectin and collagen types I III and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters. Catalytic activity: Hydrolysis of proteins including elastin by preferential cleavage: -Ala-|-Xaa- > -Val-|-Xaa-.