RHOU anticorps (Internal Region)

N° du produit ABIN350806

Cet anticorps Lapin Polyclonal détecte spécifiquement RHOU dans WB et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour RHOU anticorps (Internal Region) (ABIN350806)

Antigène: RHOU (Ras Homolog Gene Family, Member U (RHOU))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RHOU est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-RHOU anticorps

Épitope: Internal Region

Fonction: Rabbit antibody to RhoU

Specificité: Specific for RhoU.

Réactivité croisée: Humain, Souris, Rat

Réactivité croisée (Details): Other species not yet tested.

Purification: IgG

Immunogène: A synthetic peptide from the internal region of human Rho related GTP binding protein RhoU (CDC42 like GTPase 1 CDC42L1 Ryu GTPase) conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 90% identity with rat and mouse sequence.

Isotype: IgG

Information d'application

Indications d'application: IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Détails sur RHOU

Antigène: RHOU (Ras Homolog Gene Family, Member U (RHOU))

Autre désignation: RhoU

Sujet: Function: Acts upstream of PAK1 to regulate the actin cytoskeleton adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound. Subcellular location: Cell membrane, Lipid-anchor, Cytoplasmic side. Golgi apparatus membrane, Lipid-anchor. Cell junction ‰ focal adhesion. Cell projection ‰ podosome. Note: Localizes to podosomes in SRC-transformed cells. Tissue specificity: Ubiquitously expressed in all tissues examined. Expressed at high levels in the stomach small intestine brain skeletal muscle and placenta.

UniProt: Q7L0Q8