SNAP25 anticorps

N° du produit ABIN350909

L’anticorps Mouton Polyclonal anti-SNAP25 a été validé pour WB et IHC. Il convient pour détecter SNAP25 dans des échantillons de Souris.

Aperçu rapide pour SNAP25 anticorps (ABIN350909)

Antigène: SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))

Reactivité: Souris

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp SNAP25 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-SNAP25 anticorps

Fonction: Sheep antibody to SNAP-25

Specificité: Specific for SNAP-25.

Réactivité croisée: Humain, Souris, Rat

Réactivité croisée (Details): Other species not yet tested.

Purification: IgG

Immunogène: A synthetic peptide from mouse SNAP-25 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and human.

Isotype: IgG

Information d'application

Indications d'application: IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Détails sur SNAP25

Antigène: SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))

Autre désignation: SNAP-25

Sujet: FUNCTION: t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. SUBUNIT: Part of the SNARE core complex containing SNAP25 VAMP2 and STX1A. This complex binds CPLX1. Interacts with TRIM9 RIMS1 SNAP25BP and HGS. Binds STXBP6. Found in a ternary complex with STX1A and VAMP8. Found in a complex containing SYT1 SV2B and syntaxin-1. SUBCELLULAR LOCATION: Membrane, Lipid-anchor. Cell junction synapse synaptosome. Note: Membrane association requires palmitoylation. TISSUE SPECIFICITY: Neurons of the neocortex hippocampus piriform cortex anterior thalamic nuclei pontine nuclei and granule cells of the cerebellum.

UniProt: P60881

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport