SYT1 anticorps (AA 10-60)

N° du produit ABIN350924

L’anticorps Lapin Polyclonal anti-SYT1 a été validé pour WB et IHC. Il convient pour détecter SYT1 dans des échantillons de Rat.

Aperçu rapide pour SYT1 anticorps (AA 10-60) (ABIN350924)

Antigène: SYT1 (Synaptotagmin I (SYT1))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SYT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-SYT1 anticorps

Épitope: AA 10-60

Fonction: Rabbit antibody to Synaptotagmin 1 (10-60)

Specificité: Specific for SYTI.

Réactivité croisée: Souris, Rat

Réactivité croisée (Details): Other species not yet tested.

Purification: IgG

Immunogène: A synthetic peptide from AA 10-60 of rat Synaptotagmin 1 conjugated to blue carrier protein was used as the antigen. The antigen is homologous in mouse.

Isotype: IgG

Information d'application

Indications d'application: IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Détails sur SYT1

Antigène: SYT1 (Synaptotagmin I (SYT1))

Autre désignation: Synaptotagmin 1

Sujet: FUNCTION: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner, these are neurexins syntaxin and AP2. COFACTOR: Binds 3 calcium ions per subunit. The ions are bound to the C2 domains. SUBCELLULAR LOCATION: Cytoplasmic vesicle secretory vesicle synaptic vesicle. Cytoplasmic vesicle secretory vesicle chromaffin granule. Note: Synaptic vesicles and chromaffin granules. TISSUE SPECIFICITY: Predominantly expressed in rostral phylogenetically younger brain regions and in some endocrine tissues.

UniProt: P21707

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport