Trpl anticorps (4th Cytoplasmic Loop)

N° du produit ABIN351177

Cet anticorps anti-Trpl est un anticorps Lapin Polyclonal détectant Trpl dans IHC et WB. Adapté pour Drosophila melanogaster.

Aperçu rapide pour Trpl anticorps (4th Cytoplasmic Loop) (ABIN351177)

Antigène: Trpl (Transient Receptor Potential-Like (Trpl))

Reactivité: Drosophila melanogaster

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Trpl est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Détail du produit anti-Trpl anticorps

Épitope: 4th Cytoplasmic Loop

Fonction: Rabbit antibody to drosophila TRPL

Specificité: Specific for TRPL.

Réactivité croisée: Drosophila melanogaster

Réactivité croisée (Details): Other species not yet tested.

Purification: IgG

Immunogène: A synthetic peptide from 4th cytoplasmic loop of drosophila TRPL (Transient receptor potential like protein) conjugated to an immunogenic carrier protein was used as the immunogen.

Isotype: IgG

Information d'application

Indications d'application: IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Détails sur Trpl

Antigène: Trpl (Transient Receptor Potential-Like (Trpl))

Autre désignation: TRPL

Sujet: FUNCTION: A light-sensitive calcium channel that is required for inositide-mediated Ca(2+) entry in the retina during phospholipase C (PLC)-mediated phototransduction. Required for vision in the dark and in dim light. Binds calmodulin. Trp and trpl act together in the light response although it is unclear whether as heteromultimers or distinct units. Also forms a functional cation channel with trp-gamma. Activated by fatty acids metabolic stress inositols and GTP-binding proteins. SUBUNIT: Forms heteromultimers with trp-gamma and to a lower extent with trp. Interacts with FKBP59 in vivo and is found in the inaD signaling complex. SUBCELLULAR LOCATION: Membrane, Multi-pass membrane protein. Note: In the dark there is 20 fold more rhabdomeral trpl protein forming plasma membrane channels than in the light. In the light the protein translocates to an intracellular compartment. Protein levels remain unchanged in light and dark conditions.

UniProt: P48994

Pathways: Sensory Perception of Sound, Phototransduction