VPS29 anticorps (C-Term)

N° du produit ABIN351326

L’anticorps Lapin Polyclonal anti-VPS29 a été validé pour WB et IHC. Il convient pour détecter VPS29 dans des échantillons de Souris.

Aperçu rapide pour VPS29 anticorps (C-Term) (ABIN351326)

Antigène: VPS29 (Vacuolar Protein Sorting 29 (VPS29))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VPS29 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-VPS29 anticorps

Épitope: C-Term

Fonction: Rabbit antibody to VPS29

Specificité: Specific for VPS29.

Réactivité croisée: Humain, Souris, Rat

Réactivité croisée (Details): Other species not yet tested.

Purification: IgG

Immunogène: A synthetic peptide from the c-terminal region of mouse VPS29 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat human chicken zebra fish and xenopus.

Isotype: IgG

Information d'application

Indications d'application: IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Détails sur VPS29

Antigène: VPS29 (Vacuolar Protein Sorting 29 (VPS29))

Autre désignation: VPS29

Sujet: FUNCTION: Essential component of the retromer complex a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro). Has no activity towards p-nitrophenylphosphate p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro). CATALYTIC ACTIVITY: O-phospho-L(or D)-serine + H2O = L(or D)-serine + phosphate. COFACTOR: Binds 2 zinc ions per subunit. SUBCELLULAR LOCATION: Cytoplasm. Membrane, Peripheral membrane protein. Endosome membrane, Peripheral membrane protein.

UniProt: Q9QZ88