DEFA5 anticorps (cleaved)

N° du produit ABIN356090

L’anticorps Souris Monoclonal anti-DEFA5 a été validé pour IHC. Il convient pour détecter DEFA5 dans des échantillons de Humain.

Aperçu rapide pour DEFA5 anticorps (cleaved) (ABIN356090)

Antigène: DEFA5 (Defensin, alpha 5, Paneth Cell-Specific (DEFA5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DEFA5 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: 8C8

Détail du produit anti-DEFA5 anticorps

Épitope: cleaved

Réactivité croisée: Humain

Purification: Aff - Purified

Immunogène: Full-length proHD5 protein. [Swiss-Prot# Q01523] The propeptide is the full-length protein. In the mature form, it is cleaved at residue 63 (alanine).

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: -20 °C

Détails sur DEFA5

Antigène: DEFA5 (Defensin, alpha 5, Paneth Cell-Specific (DEFA5))

Autre désignation: Defensin 5

Sujet: Human neutrophil alpha-defensins (also designated HNPs) are small, cationic, cysteine-rich antimicrobial proteins that play important roles in innate immunity against infectious microbes such as bacteria, fungi and enveloped viruses. Alpha-defensins are synthesized as inactive precursors and are activated by proteolytic cleavage by MMP-7. Paneth cells in small intestinal crypts secrete the alpha-defensins, which are also termed cryptidins in mice. Alpha-defensins 5 and 6 probably contribute to innate defense of the GI mucosal surface by protecting against microbial invasion in states of intestinal inflammation.

UniProt: Q01523