DEFA5 anticorps (cleaved)

N° du produit ABIN356090

Détail du produit anti-DEFA5 anticorps

Antigène: DEFA5 (Defensin, alpha 5, Paneth Cell-Specific (DEFA5))

Épitope: cleaved

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DEFA5 est non-conjugé

Application: Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Aff - Purified

Immunogène: Full-length proHD5 protein. [Swiss-Prot# Q01523] The propeptide is the full-length protein. In the mature form, it is cleaved at residue 63 (alanine).

Clone: 8C8

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: -20 °C

Détails sur DEFA5

Antigène: DEFA5 (Defensin, alpha 5, Paneth Cell-Specific (DEFA5))

Autre désignation: Defensin 5 (DEFA5 Produits)

Synonymes: anticorps DEF5, anticorps HD-5, anticorps Defa29, anticorps Defcr29, anticorps Defcr5, anticorps DEFA1, anticorps DEFA5, anticorps Defa, anticorps defensin alpha 5, anticorps defensin, alpha, 5, anticorps defensin, alpha 5, Paneth cell-specific, anticorps alpha-defensin 1A, anticorps DEFA5, anticorps Defa5, anticorps MNP1A

Sujet: Human neutrophil alpha-defensins (also designated HNPs) are small, cationic, cysteine-rich antimicrobial proteins that play important roles in innate immunity against infectious microbes such as bacteria, fungi and enveloped viruses. Alpha-defensins are synthesized as inactive precursors and are activated by proteolytic cleavage by MMP-7. Paneth cells in small intestinal crypts secrete the alpha-defensins, which are also termed cryptidins in mice. Alpha-defensins 5 and 6 probably contribute to innate defense of the GI mucosal surface by protecting against microbial invasion in states of intestinal inflammation.

UniProt: Q01523