Factor Inhibiting HIF-1 Antibody (Extracellular Domain), (N-Term) anticorps

N° du produit ABIN356096

L’anticorps anti-Factor Inhibiting HIF-1 Antibody Polyclonal Lapin est utilisé pour la détection de Factor Inhibiting HIF-1 Antibody dans des échantillons de Souris et Rat. Il a été validé pour ICC, IHC et WB.

Aperçu rapide pour Factor Inhibiting HIF-1 Antibody (Extracellular Domain), (N-Term) anticorps (ABIN356096)

Antigène: Factor Inhibiting HIF-1 Antibody

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Application: Immunocytochemistry (ICC), Immunohistochemistry (IHC), Western Blotting (WB)

Détail du produit

Épitope: Extracellular Domain, N-Term

Réactivité croisée: Souris, Rat (Rattus)

Purification: Aff - Purified

Immunogène: Synthetic peptide (Rat) from the N-terminal extracellular domain conjugated to immunogenic carrier protein.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Stock: -20 °C

Détail du antigène

Antigène: Factor Inhibiting HIF-1 Antibody

Classe de substances: Antibody

Sujet: Factor Inhibiting HIF1 (FIH) protein facilitates repression of HIF-1 transcriptional activity by binding to VHL, which acts as a transcriptional corepressor. VHL inhibits HIF-1 alpha transactivation function by recruiting histone deacetylases. Involvement of VHL in association with FIH provides a unifying mechanism for the modulation of HIF-1 alpha protein stabilization and transcriptional activation in response to changes in cellular oxygen concentration.