PERP anticorps (C-Term)
Aperçu rapide pour PERP anticorps (C-Term) (ABIN356105)
Antigène
Voir toutes PERP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Réactivité croisée
- Humain
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Purification
- affinity purified
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Immunogène
- Synthetic peptide corresponding to AA near the carboxy terminus of human PERP, which differ from the mouse sequence by three AA (7-9).
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Stock
- -20 °C
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- PERP (TP53 Apoptosis Effector (PERP))
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Autre désignation
- PERP/TP53 Apoptosis Effector Protein
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Sujet
- The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. PERP (TP53 Apoptosis Effector) is a plasma membrane protein. p53 binds to the promoter of PERP and transcriptionally activates PERP gene then the translated PERP protein mediates the p53 induced apoptosis. The expression of PERP causes cell death. PERP is a mediator of p53 induced apoptosis. PERP has sequence similarity to PMP-22/gas3 and is a new member of the PMP-22/gas3 family.
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Pathways
- Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity
Antigène
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