Keratin 10 anticorps

N° du produit ABIN356290

Cet anticorps Souris Monoclonal détecte spécifiquement Keratin 10 dans IF et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour Keratin 10 anticorps (ABIN356290)

Antigène: Keratin 10 (KRT10)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Keratin 10 est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: CK208

Détail du produit anti-Keratin 10 anticorps

Specificité: This antibody recognises Cytokeratin 10+13 (CK10+13). It reacts with 53 kDa and 56.6 kDa cytokeratin (CK) proteins by Western blot. With frozen sections, this antibody serves as a differentiation related marker for all stratified epithelia and stains all suprabasal cell in both cornifying and non-cornifying stratified epithelia and more differentiated cells of squamous carcinomas.
Cellular Localization: Cytoplasmic.

Réactivité croisée (Details): Also reacts to: KRT13

Attributs du produit: Synonyms: Cytokeratin-10, CK10, CK-10, Keratin-10, KRT10, KPP, K10, Keratin, Type I Cytoskeletal 10

Purification: Purified

Immunogène: Cytokeratin extraction from human ectocervical epithelium. Remarks: Molecular weight of antigen: CK10 is 56. 9 kDa and CK13 is 53 kDa.

Isotype: IgG2a

Information d'application

Indications d'application: Suitable for Immunohistochemistry and Immunocytochemistry (Frozen tissue sections onlyor cell smears). For IHC dilute concentared antibody at 1/50-1/100, use streptavidinapprox. biotin system orpolymer system, incubate 30 minutes at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: PBS, pH 7.4 containing 1 % BSA as stabilizer and 0.05 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Storethe antibody undiluted at 2-8 °Cfor one month or (in aliquots) at -28 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Date de péremption: 12 months

Détails sur Keratin 10

Antigène: Keratin 10 (KRT10)

Autre désignation: Cytokeratin 10

Sujet: Cytokeratins are intermediate filament keratins found in the intracytoplasmic cytoskeleton of epithelial tissue There are two types of Cytokeratins: the low weight, acidic type I cytokeratins and the high weight, basic or neutral type II. Cytokeratins are usually found in pairs comprising a type I Cytokeratin and a type II cytokeratin. The high molecular weight cytokeratins, which are the basic or neutral cytokeratins, comprise subtypes CK1, CK2, CK3, CK4, CK5, CK6, CK7, CK8 and CK9. The low molecular weight cytokeratins, which are the acidic cytokeratins, comprise subtypes CK10, CK12, CK 13, CK14, CK16, CK17, CK18, CK19 and CK20. Recently Silveira et. al. (3) have reported that in tongue squamous cell carcinoma the expression of CK 10 was significantly correlated with the presence of metasis.Synonyms: CK-10, CK10, Cytokeratin-10, K10, KPP, KRT10, Keratin, Keratin-10, Type I Cytoskeletal 10

ID gène: 3858

UniProt: P13645