LIN28A anticorps
Aperçu rapide pour LIN28A anticorps (ABIN356385)
Antigène
Voir toutes LIN28A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody is specific to LIN28A.
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Attributs du produit
- Synonyms: LIN-28, LIN28A, CSDD1, ZCCHC1, Lin-28 homolog A
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Purification
- Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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Immunogène
- LIN28A recombinant protein is used to produce this monoclonal antibody.
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Isotype
- IgG1
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Indications d'application
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ELISA: 1/10000. Western blotting: 1/200-1/2000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Date de péremption
- 12 months
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- LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))
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Autre désignation
- LIN28
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Sujet
- LIN28A acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. Binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. It is essential for skeletal muscle differentiation through the translational up-regulation of IGF2 expression.Synonyms: CSDD1, LIN-28, LIN28A, Lin-28 homolog A, ZCCHC1
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ID gène
- 79727
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UniProt
- Q9H9Z2
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Pathways
- Stem Cell Maintenance
Antigène
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