Transferrin anticorps

N° du produit ABIN356489

L’anticorps anti-Transferrin Polyclonal Lapin est utilisé pour la détection de Transferrin dans des échantillons de Humain. Il a été validé pour IP et EIA.

Aperçu rapide pour Transferrin anticorps (ABIN356489)

Antigène: Transferrin (TF)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Transferrin est non-conjugé

Application: Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Détail du produit anti-Transferrin anticorps

Specificité: This antibody is specific for Transferrin (TF).

Purification: Protein A Chromatography.

Immunogène: Purified human transferrin.

Isotype: IgG

Information d'application

Indications d'application: Suitable for use in Immunoprecipitation and ELISA (1/1,000-1/10,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 2.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.05 % Sodium Azide as preservative and 1 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur Transferrin

Antigène: Transferrin (TF)

Sujet: Transferrin is a blood plasma protein for iron ion delivery. It is a is a glycoprotein, which binds iron very tightly but reversibly. Transferrin has a molecular weight of around 80 kilo Daltons and contains 2 specific high affinity Fe (III) binding sites. It is synthesized in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. The iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/Transferrin is essential in hemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. When a transferrin protein loaded with iron encounters a transferrin receptor on the surface of a cell (importantly, to erythroid precursors in the bone marrow), it binds to it and is consequently transported into the cell in a vesicle.Synonyms: Beta-1 metal-binding globulin, Serotransferrin, Siderophilin

ID gène: 7018

NCBI Accession: NP_001054

UniProt: P02787

Pathways: Transition Metal Ion Homeostasis