DNMT3L anticorps (AA 392-421)
Aperçu rapide pour DNMT3L anticorps (AA 392-421) (ABIN356591)
Antigène
Voir toutes DNMT3L (TRDMT1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 392-421
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Specificité
- This antibody is specific to Mouse Dnmt3L. It may recognize the Human homolog (44 kDa)
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Réactivité croisée (Details)
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Species reactivity (expected):Human.
Species reactivity (tested):Mouse. -
Purification
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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Immunogène
- KLH conjugated synthetic peptide between 392~421 amino acids from the Mouse Dnmt3L sequence within the last 100 aa.
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Isotype
- Ig Fraction
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Indications d'application
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ELISA: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))
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Autre désignation
- DNMT3L
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Sujet
- MDnmt3L (DNA methyltransferase 3L) does not appear to be catalytically active due to loss of the critical active site residues. It may function not directly as a DNA methyltransferase but rather as a regulator of methylation at imprinted loci. It is required specifically for the establishment of genomic imprints but is dispensable for their propagation. It is essential for the de novo methylation of single-copy DNA sequences. The protein is well-express in testis, thymus, ovary, and heart. mDnmt3L, which belongs to the 5-cytosine methyltransferase family, contains 1 ADD-type zinc finger.Synonyms: DNA (cytosine-5)-methyltransferase 3-like
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ID gène
- 54427, 10090
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UniProt
- Q9CWR8
Antigène
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