HAT1 anticorps (C-Term)

N° du produit ABIN356621

L’anticorps Lapin Polyclonal anti-HAT1 a été validé pour WB et EIA. Il convient pour détecter HAT1 dans des échantillons de Humain.

Aperçu rapide pour HAT1 anticorps (C-Term) (ABIN356621)

Antigène: HAT1 (Histone Acetyltransferase 1 (HAT1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HAT1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-HAT1 anticorps

Épitope: AA 390-419, C-Term

Specificité: This antibody is specific to Human HAT1 (C-term).

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: KLH conjugated synthetic peptide between 390~419 amino acids from the C-terminal region of Human HAT1

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur HAT1

Antigène: HAT1 (Histone Acetyltransferase 1 (HAT1))

Autre désignation: HAT1

Sujet: Histone acetylation, particularly of histone H4, has been proposed to play an important role in replication-dependent nucleosome assembly. The HAT1 protein contains D, A, and B motifs, which are present in many N-acetyltransferases, including those that acetylate substrates other than histones. The HAT1 holoenzyme consists of 2 subunits: the catalytic 46-kD HAT1 and the accessory p46. The p46 subunit stimulated the activity of HAT1 and bound to core histones. The HAT1 holoenzyme acetylated newly synthesized but not nucleosomal histone H4 at lys5 and lys12, and, to a lesser extent, histone H2A at lys5. HAT1 and p46 polypeptides are located in the nucleus of S-phase cells. HAT1 may play a role in telomeric silencing.Synonyms: Histone acetyltransferase type B catalytic subunit

ID gène: 8520, 9606

UniProt: O14929