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SETD8 anticorps (C-Term)
SETD8
Reactivité: Humain
WB, EIA
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-SETD8 anticorps
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Antigène
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SETD8
(SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))
Épitope
Tous les épitopes à travers SETD8 Anticorps.
AA 364-393, C-Term
Reactivité
Toutes les réactivités sur SETD8 Anticorps
Humain
Hôte
Toutes les hôtes sur SETD8 Anticorps
Lapin
Clonalité
Toutes les clonalités sur SETD8 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers SETD8 Anticorps
Cet anticorp SETD8 est non-conjugé
Application
Tous les applications à travers SETD8 Anticorps.
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificité
This antibody is specific to Human SETD8 / SET07 (C-term)
Purification
Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogène
KLH conjugated synthetic peptide between 364~393 amino acids from the C-terminal region of human SET07
Isotype
Ig Fraction
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Alternatives
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Information d'application
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Indications d'application
ELISA: 1/1,000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Détails sur SETD8
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Antigène
SETD8
(SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))
Autre désignation
SETD8 / SET07 (SETD8 Produits )
Synonymes
anticorps KMT5A, anticorps PR-Set7, anticorps SET07, anticorps SET8, anticorps 2410195B05Rik, anticorps AA617402, anticorps AW536475, anticorps PR-SET7, anticorps setd8b, anticorps wu:fc23f12, anticorps zgc:171649, anticorps Pr-set7, anticorps RGD1305893, anticorps Setd8, anticorps kmt5a, anticorps kmt5a-a, anticorps setd8, anticorps setd8-a, anticorps set8a, anticorps setd8a, anticorps wu:fj33f02, anticorps zgc:153719, anticorps lysine methyltransferase 5A, anticorps lysine methyltransferase 5Ab, anticorps lysine methyltransferase 5A S homeolog, anticorps lysine methyltransferase 5Aa, anticorps KMT5A, anticorps Kmt5a, anticorps kmt5ab, anticorps kmt5a.S, anticorps kmt5aa
Sujet
SET07 is a histone methyltransferase that methylates Lys-20 of histone H4. H4 Lys-20 methylation represents a specific tag for epigenetic transcriptional repression. The nuclear SET07 protein, which associates with silent chromatin on euchromatic arms but shows no association with constitutive heterochromatin, prefers nucleosomes as substrate compared to free histones. It appears that SET07 may play a role in maintaining silent chromatin by preventing neighboring acetylation of H4 tail. Although the SET domain contains the active site of enzymatic activity, both sequences upstream and downstream of the SET domain are required for methyltransferase activity.Synonyms: H4-K20-HMTase SETD8, Histone-lysine N-methyltransferase SETD8, KMT5A, Lysine N-methyltransferase 5A, PR-Set7, PR/SET domain-containing protein 07, PRSET7, SET domain-containing protein 8, SET8
ID gène
387893, 9606
UniProt
Q9NQR1
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