PRDM2 anticorps (AA 245-573)
Aperçu rapide pour PRDM2 anticorps (AA 245-573) (ABIN356710)
Antigène
Voir toutes PRDM2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 245-573
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Specificité
- This antibody also recognizes the isoform beta (Riz2) of PRDM2 (185 kDa)
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Purification
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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Immunogène
- Purified recombinant GST fusion protein encoding aa 245-573 of Rat Riz1. Genename: PRDM2
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Isotype
- Ig Fraction
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Indications d'application
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ELISA: 1/1,000. Western Blot.1/100-1/500. Immunohistochemistry: 1/100-1/500. Immunoprecipitation: 1 μg Pab/100 μg cell lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))
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Autre désignation
- PRDM2
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Sujet
- PRDM2 is a 250-kD nuclear protein containing 8 zinc finger motifs. It contains an RB-binding motif that is related to that of the adenovirus E1A oncoprotein, RIZ also shares an antigenic epitope with the C terminus of E1A. It is expressed in human retinoblastoma cells and at low levels in all other human cell lines examined. Using fluorescence in situ hybridization, the PRDM2 gene has been mapped to 1p36. PRDM2 may be a candidate target of 1p36 alterations that commonly occur in neuroendocrine, breast, liver, colon, skin, and lymphoid tumors.Synonyms: GATA-3-binding protein G3B, HUMHOXY1, KMT8, Lysine N-methyltransferase 8, MTB-ZF, MTE-binding protein, PR domain zinc finger protein 2, RIZ1, RIZ2, Retinoblastoma protein-interacting zinc finger protein
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ID gène
- 7799, 5874
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UniProt
- Q13029
Antigène
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