TXN anticorps (N-Term)
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- Antigène Voir toutes TXN Anticorps
- TXN (Thioredoxin (TXN))
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Épitope
- N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TXN est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody is specific to Thioredoxin (TRX) (N-term).
- Réactivité croisée (Details)
- Species reactivity (tested):Human.
- Purification
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Immunogène
- KLH conjugated synthetic peptide selected from the N-terminal region of Human TrX.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product TXN Anticorps primaire
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- Indications d'application
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ELISA: 1/1,000. Western blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Antigène
- TXN (Thioredoxin (TXN))
- Autre désignation
- Thioredoxin / TRX1 (TXN Produits)
- Synonymes
- anticorps TRDX, anticorps TRX, anticorps TRX1, anticorps ADF, anticorps AW550880, anticorps Trx1, anticorps Txn, anticorps trx, anticorps TXN, anticorps SCM1.18, anticorps trxA3, anticorps thioredoxin, anticorps TR-1, anticorps Trx-1, anticorps thioredoxin, anticorps thioredoxin 1, anticorps thioredoxin L homeolog, anticorps similar to 44RRORF109c hypothetical protein; similar to bacterial thioredoxin (SwissProt P06544), anticorps thioredoxin pseudogene, anticorps cytosolic thioredoxin Trx1, anticorps TXN, anticorps Txn1, anticorps txn.L, anticorps txn, anticorps trx, anticorps SCO0885, anticorps PHG25ORF099c, anticorps LOC100349046, anticorps Txn, anticorps trx1
- Sujet
- Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells. Trx contains a redox active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds. Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor. The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations. Specific protein disulfide targets for reduction by Trx include protein disulfide isomerase(PDI) and a number of transcription factors such as p53, NF-kB and AP-1.Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.Synonyms: ADF, ATL-derived factor, SASP, Surface-associated sulphydryl protein, TRDX, TRX, TXN
- Poids moléculaire
- 11737 Da
- ID gène
- 7295, 9606
- UniProt
- P10599
- Pathways
- Carbohydrate Homeostasis, Cell RedoxHomeostasis
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