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HNMT anticorps (N-Term)

L’anticorps Lapin Polyclonal anti-HNMT a été validé pour WB, IHC (p) et EIA. Il convient pour détecter HNMT dans des échantillons de Humain.
N° du produit ABIN356933

Aperçu rapide pour HNMT anticorps (N-Term) (ABIN356933)

Antigène

Voir toutes HNMT Anticorps
HNMT (Histamine N-Methyltransferase (HNMT))

Reactivité

  • 34
  • 6
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 27
  • 6
  • 1
Lapin

Clonalité

  • 29
  • 5
Polyclonal

Conjugué

  • 22
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp HNMT est non-conjugé

Application

  • 27
  • 14
  • 14
  • 7
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Épitope

    • 9
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Specificité

    This antibody detects HNMT at N-term.

    Purification

    Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    Immunogène

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human HNMT.

    Isotype

    Ig Fraction
  • Indications d'application

    ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry 1: 10 - 1: 50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.25 mg/mL

    Buffer

    PBS with 0.09 % (W/V) sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Antigène

    HNMT (Histamine N-Methyltransferase (HNMT))

    Autre désignation

    HNMT / HMT

    Sujet

    In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. HNMT is the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells.Synonyms: Histamine N-methyltransferase

    Poids moléculaire

    33295 Da

    ID gène

    3176, 9606

    UniProt

    P50135
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