PYGM anticorps (C-Term)

N° du produit ABIN356948

L’anticorps Lapin Polyclonal anti-PYGM a été validé pour WB et EIA. Il convient pour détecter PYGM dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour PYGM anticorps (C-Term) (ABIN356948)

Antigène: PYGM (Phosphorylase, Glycogen, Muscle (PYGM))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PYGM est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-PYGM anticorps

Épitope: C-Term

Specificité: This antibody detects PYGM at C-term.

Purification: Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PYGM.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 10 - 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-PYGM (ABIN356948)

Hathout, Marathi, Rayavarapu, Zhang, Brown, Seol, Gordish-Dressman, Cirak, Bello, Nagaraju, Partridge, Hoffman, Takeda, Mah, Henricson, McDonald: "Discovery of serum protein biomarkers in the mdx mouse model and cross-species comparison to Duchenne muscular dystrophy patients." dans: Human molecular genetics, Vol. 23, Issue 24, pp. 6458-69, (2015) (PubMed).

Détails sur PYGM

Antigène: PYGM (Phosphorylase, Glycogen, Muscle (PYGM))

Autre désignation: Glycogen Phosphorylase Muscle Form

Sujet: PYGM catalyzes and regulates the breakdown of glycogen to glucose-1-phosphate. Defects in PYGM are the cause of glycogen storage disease type 5 (GSD5), also known as McArdle disease. GSD5 is a metabolic disorder resulting in myopathy characterized by exercise intolerance, cramps, muscle weakness and recurrent myoglobinuria.Synonyms: GPMM, Myophosphorylase, PYGM, Phosphorylase A, Phosphorylase B

Poids moléculaire: 97092 Da

ID gène: 5837, 9606

UniProt: P11217

Pathways: Cellular Glucan Metabolic Process