Connexin 31 anticorps (C-Term)

N° du produit ABIN357088

Détail du produit anti-Connexin 31 anticorps

Antigène: Connexin 31 (GJB3) (Gap Junction Protein, beta 3, 31kDa (GJB3))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Connexin 31 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects Connexin 31 (GJB3) at C-term.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human GJB3.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA 1: 1,000. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Détails sur Connexin 31

Antigène: Connexin 31 (GJB3) (Gap Junction Protein, beta 3, 31kDa (GJB3))

Autre désignation: GJB3 / Cx31 (GJB3 Produits)

Synonymes: anticorps CX31, anticorps DFNA2, anticorps DFNA2B, anticorps EKV, anticorps Cnx31, anticorps Cx31, anticorps D4Wsu144e, anticorps Gjb-3, anticorps ekv, anticorps cx31, anticorps dfna2, anticorps gjb3b, anticorps dfna2b, anticorps connexin-31, anticorps gap junction protein beta 3, anticorps gap junction protein, beta 3, anticorps gap junction protein beta 3 L homeolog, anticorps GJB3, anticorps Gjb3, anticorps gjb3.L, anticorps gjb3

Sujet: Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. Defects in GJB3 have been linked to erythrokeratodermia variabilis (EKV) is an autosomal dominant genodermatosis characterized by transient figurate red patches or hyperkeratosis. Mutations in GJB2 have also been associated with genetically derived hearing impairments, including autosomal recessive nonsyndromic deafness.Synonyms: Connexin-31, Gap junction beta-3 protein

Poids moléculaire: 30818 Da

ID gène: 2707, 9606

UniProt: O75712

Pathways: Sensory Perception of Sound