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ASCL1 anticorps (C-Term)

ASCL1 Reactivité: Humain, Souris WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN357401
  • Antigène Voir toutes ASCL1 Anticorps
    ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
    Épitope
    • 20
    • 15
    • 9
    • 8
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 84
    • 44
    • 28
    • 9
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    Humain, Souris
    Hôte
    • 84
    • 6
    • 2
    Lapin
    Clonalité
    • 86
    • 6
    Polyclonal
    Conjugué
    • 40
    • 11
    • 9
    • 9
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ASCL1 est non-conjugé
    Application
    • 79
    • 60
    • 28
    • 13
    • 13
    • 11
    • 4
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects ASCL1 (Achaete-scute homolog 1) at C-term.
    Purification
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogène
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human Hash1.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ASCL1 Anticorps primaire
  • Indications d'application
    ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
    Autre désignation
    ASCL1 (ASCL1 Produits)
    Synonymes
    anticorps ASH1, anticorps HASH1, anticorps MASH1, anticorps bHLHa46, anticorps AI225900, anticorps Mash1, anticorps ASCL1, anticorps Zash-1a, anticorps ash, anticorps asha, anticorps id:ibd5085, anticorps im:7138587, anticorps si:dkey-264k15.2, anticorps zash1a, anticorps zasha, anticorps Xash1, anticorps ascl1-A, anticorps Zash-1b, anticorps ashb, anticorps zashb, anticorps achaete-scute family bHLH transcription factor 1, anticorps achaete-scute family bHLH transcription factor 1a, anticorps achaete-scute family bHLH transcription factor 1 L homeolog, anticorps achaete-scute complex homolog 1, anticorps achaete-scute family bHLH transcription factor 1b, anticorps ASCL1, anticorps Ascl1, anticorps ascl1a, anticorps ascl1.L, anticorps LOC100220505, anticorps ascl1b
    Sujet
    ACSL1, alternatively titled Hash1 or Mash1, is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. ACSL1 plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. The protein is highly expressed in medullary thyroid cancer and small cell lung cancer and may be a useful marker for these cancers. The presence of a CAG repeat in the gene suggests it may also play a role in tumor formation.Synonyms: ASH1, Achaete-scute homolog 1, HASH1, MASH1
    Poids moléculaire
    25454 Da
    ID gène
    429
    NCBI Accession
    NP_004307
    UniProt
    P50553
    Pathways
    Dopaminergic Neurogenesis
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