Neurogenin 1 anticorps (N-Term)

N° du produit ABIN357407

L’anticorps Lapin Polyclonal anti-Neurogenin 1 a été validé pour WB, IHC (p) et EIA. Il convient pour détecter Neurogenin 1 dans des échantillons de Humain.

Aperçu rapide pour Neurogenin 1 anticorps (N-Term) (ABIN357407)

Antigène: Neurogenin 1 (NEUROG1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neurogenin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-Neurogenin 1 anticorps

Épitope: N-Term

Specificité: This antibody detects NeuroG1 at N-term.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human NeuroG1.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Détails sur Neurogenin 1

Antigène: Neurogenin 1 (NEUROG1)

Autre désignation: Neurogenin 1

Sujet: Basic helix-loop-helix (bHLH) proteins are transcription factors involved in determining cell type during development. NeuroG1 is a bHLH protein with dual cell-fate specification roles. It functions during neurogenesis, and it has also been shown to inhibit the differentiation of neural stem cells into astrocytes. NeuroG1 promotes neurogenesis by functioning as a transcriptional activator, yet it inhibits astrocyte differentiation by compartmentalizing the CREB-binding protein transcription complex away from astrocyte differentiation genes and by inhibiting STAT transcription factors essential for gliogenesis.Synonyms: NEUROD3, NGN, NGN1, Neurogenic basic-helix-loop-helix protein, Neurogenic differentiation factor 3, Neurogenin 1

Poids moléculaire: 25717 Da

ID gène: 4762

NCBI Accession: NP_006152

UniProt: Q92886