UBE2L3 anticorps (N-Term)
Aperçu rapide pour UBE2L3 anticorps (N-Term) (ABIN357493)
Antigène
Voir toutes UBE2L3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Specificité
- This antibody is specific to UBE2L3/UBCH7 (N-term). Predicted to cross react with Mouse (100 % Antigen Homology).
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Purification
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human UBE2L3.
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Isotype
- Ig Fraction
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Indications d'application
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ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))
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Autre désignation
- UBE2L3 / UBCH7
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Sujet
- The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro.Synonyms: E2-F1, L-UBC, UBCE7, Ubiquitin carrier protein L3, Ubiquitin-conjugating enzyme E2 L3, Ubiquitin-protein ligase L3
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Poids moléculaire
- 17861 Da
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ID gène
- 7332, 5874
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UniProt
- P68036
Antigène
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