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USP11 anticorps (N-Term)

USP11 Reactivité: Humain WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN357538
  • Antigène Voir toutes USP11 Anticorps
    USP11 (Ubiquitin Specific Peptidase 11 (USP11))
    Épitope
    • 22
    • 8
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    N-Term
    Reactivité
    • 62
    • 13
    • 12
    • 1
    • 1
    Humain
    Hôte
    • 56
    • 6
    • 1
    Lapin
    Clonalité
    • 47
    • 16
    Polyclonal
    Conjugué
    • 29
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp USP11 est non-conjugé
    Application
    • 42
    • 33
    • 27
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody is specific to USP11 (N-term).
    Purification
    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogène
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human USP11.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product USP11 Anticorps primaire
  • Indications d'application
    ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène
    USP11 (Ubiquitin Specific Peptidase 11 (USP11))
    Autre désignation
    USP11 (USP11 Produits)
    Synonymes
    anticorps USP11, anticorps DKFZp459L098, anticorps UHX1, anticorps 6230415D12Rik, anticorps mKIAA4085, anticorps Uhx1, anticorps ubiquitin specific peptidase 11, anticorps universal stress protein, anticorps USP11, anticorps RR_RS19935, anticorps Usp11
    Sujet
    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.Synonyms: Deubiquitinating enzyme 11, UHX1, Ubiquitin carboxyl-terminal hydrolase 11, Ubiquitin thioesterase 11, Ubiquitin-specific-processing protease 11
    Poids moléculaire
    105030 Da
    ID gène
    8237, 5874
    UniProt
    P51784
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