AGL anticorps (C-Term)
Aperçu rapide pour AGL anticorps (C-Term) (ABIN357688)
Antigène
Voir toutes AGL AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1487-1516, C-Term
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Specificité
- This antibody is specific to AGL/GDE (C-term).
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Purification
- Protein A Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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Immunogène
- KLH conjugated synthetic peptide between 1487~1516 amino acids from the C-terminal region of Human AGL
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Isotype
- Ig Fraction
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Indications d'application
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ELISA: 1/1,000. Western Blot: 1/100-1/500. This antibody is reported to work in Immunofluorescence (See: Cheng, Alan, et al. Genes &Dev.2007 Oct 01,21(19): 2399-2409).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- AGL (Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL))
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Autre désignation
- AGL / GDE
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Sujet
- AGL is a glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in the AGL gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing.Synonyms: 4-alpha-glucanotransferase, 6-glucosidase, Amylo-alpha-1, Glycogen debranching enzyme
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Poids moléculaire
- 174764 Da
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ID gène
- 178, 9606
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UniProt
- P35573
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Pathways
- Cellular Glucan Metabolic Process
Antigène
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