EZH1 anticorps (Middle Region)

N° du produit ABIN357745

Cet anticorps Lapin Polyclonal détecte spécifiquement EZH1 dans WB, IHC (p) et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour EZH1 anticorps (Middle Region) (ABIN357745)

Antigène: EZH1 (Enhancer of Zeste Homolog 1 (EZH1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EZH1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-EZH1 anticorps

Épitope: Middle Region

Specificité: This antibody is specific to EZH1 (Center).

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human EZH1.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western Blot: 1/50-1/100. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur EZH1

Antigène: EZH1 (Enhancer of Zeste Homolog 1 (EZH1))

Autre désignation: EZH1

Sujet: EZH1 encodes a protein of 747 amino acids that displays 55 % amino acid identity overall with the Drosophila homolog.1 The strong sequence conservation suggested potential roles for EZH1 in human development as a transcriptional regulator and as a component of protein complexes that preserve heterochromatin stability. EZH1 is expressed as 2 major transcripts in all adult and fetal human tissues evaluated.. Analysis of an EZH1 cDNA revealed an unusual splicing event involving EZH1 and a tandemly linked gene GPR2 and suggested a potential mechanism for modifying the EZH1 protein in the conserved C-terminal domain. The GPR2 gene maps to 17q21.1-q21.3 in the vicinity of the BRCA1 gene.Synonyms: ENX-2, Enhancer of zeste homolog 1, Histone-lysine N-methyltransferase EZH1, KIAA0388

Poids moléculaire: 85270 Da

ID gène: 2145, 9606

UniProt: Q92800