ACSL6 anticorps (Middle Region)

N° du produit ABIN357782

L’anticorps Lapin Polyclonal anti-ACSL6 a été validé pour WB, IHC (p) et EIA. Il convient pour détecter ACSL6 dans des échantillons de Humain et Souris.

Aperçu rapide pour ACSL6 anticorps (Middle Region) (ABIN357782)

Antigène: ACSL6 (Acyl-CoA Synthetase Long-Chain Family Member 6 (ACSL6))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACSL6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-ACSL6 anticorps

Épitope: Middle Region

Specificité: This antibody is specific to FACL6 (Center).

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human FACL6.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur ACSL6

Antigène: ACSL6 (Acyl-CoA Synthetase Long-Chain Family Member 6 (ACSL6))

Autre désignation: ACSL6

Sujet: FACL6 is involved in activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. It plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid. FACL6 is expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derieved from fetal liver, haemopoietic stem cells from cord blood, bone marrow, and brain. Expression is low at earlier stages of erythroid development but is very high in reticulocytes. This protein is involved in myelodysplastic syndrome (MDS) with basophilia, acute myelogenous leukemia (AML) with eosinophilia, and acute eosinophilic leukemia (AEL). It is characterized by a chromosomal translocation t(5,12)(q31,p13) that involves ETV6 and ACSL6.Synonyms: ACS2, FACL6, KIAA0837, LACS5, Long-chain acyl-CoA synthetase 6, Long-chain-fatty-acid--CoA ligase 6

Poids moléculaire: 77680 Da

ID gène: 23305, 5874

UniProt: Q9UKU0