PAPSS1 anticorps (C-Term)

N° du produit ABIN357814

Détail du produit anti-PAPSS1 anticorps

Antigène: PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate Synthase 1 (PAPSS1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAPSS1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects PAPSS1 (C-term).

Purification: Purified

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PAPSS1.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western Blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur PAPSS1

Antigène: PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate Synthase 1 (PAPSS1))

Autre désignation: PAPSS1 (PAPSS1 Produits)

Synonymes: anticorps ATPSK1, anticorps PAPSS, anticorps SK1, anticorps AI325286, anticorps Asapk, anticorps papss1, anticorps MGC82588, anticorps atpsk1, anticorps papss, anticorps sk1, anticorps PAPSS1, anticorps wu:fc43e12, anticorps zgc:194984, anticorps zgc:194985, anticorps CG8363, anticorps DmPAPSS, anticorps Dmel\\CG8363, anticorps PAPS, anticorps Paps, anticorps l(3)76BDn, anticorps paps, anticorps 3'-phosphoadenosine 5'-phosphosulfate synthase 1, anticorps bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1, anticorps bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2, anticorps PAPS synthetase, anticorps PAPSS1, anticorps Papss1, anticorps papss1, anticorps papss1.L, anticorps LOC100543301, anticorps LOC100637112, anticorps Papss

Sujet: Sulfotransferase (SULT) enzymes catalyze the sulfate conjugation of many drugs, xenobiotic compounds, hormones, and neurotransmitters. 3'-phosphoadenosine 5'-phosphosulfate (PAPS) synthase (PAPSS) catalyzes the biosynthesis of PAPS which serves as the universal sulfonate donor compound for all sulfotransferase reactions. In humans, PAPS is synthesized from adenosine 5-prime triphosphate (ATP) and inorganic sulfate by 2 isoforms, PAPSS1 and PAPSS2 (603005). Bifunctional PAPSS1 is comprised of an N-terminal APS kinase domain, and a C-terminal ATP sulfurylase domain. Full-length protein has significantly less APS kinase activity than the N-terminal fragment, suggesting that the C-terminal domain exerts a regulatory role on the N-terminal APS kinase activity. In humans there are two major isoforms: PAPSS1 and PAPSS2. In brain and skin PAPSS1 is the major isoform, whereas in liver, cartilage and adrenal glands PAPSS2 isoform expression dominates. The predicted 623-amino acid protein is 98 % identical to mouse PAPS synthase. The N-terminal 268-amino acid region of human PAPS synthase resembles APS kinases from other organisms and contains 3 conserved nucleotide-binding motifs.Synonyms: ATPSK1, Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1, PAPSS, PAPSS 1, SK1, Sulfurylase kinase 1

Poids moléculaire: 70833 Da

ID gène: 9061, 9606

UniProt: O43252

Pathways: Glycosaminoglycan Metabolic Process, Ribonucleoside Biosynthetic Process