M6PR anticorps (N-Term)

N° du produit ABIN357957

Détail du produit anti-M6PR anticorps

Antigène: M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp M6PR est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects M6PR (N-term).

Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-term region of human M6PR.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Références pour anticorps anti-M6PR (ABIN357957)

Ohka, Tan, Ishiyama, Ogasawara, Hanasaka, Ishida, Hagiwara, Liu, Chong, Hanaki, Schiavo: "The uncoating of EV71 in mature late endosomes requires CD-M6PR." dans: Biology open, Vol. 11, Issue 9, (2022) (PubMed).

Détails sur M6PR

Antigène: M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Autre désignation: M6PR (M6PR Produits)

Sujet: M6PR is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.Synonyms: 46 kDa mannose 6-phosphate receptor, CD Man-6-P receptor, CD-MPR, Cation-dependent mannose-6-phosphate receptor, MPR46, MPRD

Poids moléculaire: 30993 Da

ID gène: 4074, 9606

UniProt: P20645