MLLT1
Reactivité: Humain
IHC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Antigène
MLLT1
(MLLT1, super elongation complex subunit (MLLT1))
anticorps MGC84026, anticorps MLLT1, anticorps ENL, anticorps LTG19, anticorps YEATS1, anticorps AA407901, anticorps BAM11, anticorps MLLT1, super elongation complex subunit, anticorps myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 L homeolog, anticorps myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1, anticorps Mllt1, anticorps MLLT1, anticorps mllt1.L, anticorps mllt1
Sujet
Chromosome band 11q23 is the site of translocations in myeloid and lymphoid acute leukemias, pediatric leukemias, and treatment-induced secondary acute myelogenous leukemia. The translocation breakpoints cluster in a restricted region of the HRX gene resulting in chimeric genes that encode an N-terminal portion of Hrx fused to various partner proteins. Myeloid/lymphoid or mixed-lineage leukemia translocated to 1 (MLLT1) is a nuclear protein with transcriptional transactivation properties that is fused to Hrx in t(11,19) leukemias. The minimal MLLT1 sequence required for transcription activation was narrowed to the C-terminal 90 amino acids.Synonyms: LTG19, YEATS domain-containing protein 1, YEATS1, mixed-lineage leukemia translocated to 1