OASL anticorps (C-Term)

N° du produit ABIN358720

Détail du produit anti-OASL anticorps

Antigène: OASL (2'-5'-Oligoadenylate Synthetase-Like (OASL))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OASL est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to OASL.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human OASL.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur OASL

Antigène: OASL (2'-5'-Oligoadenylate Synthetase-Like (OASL))

Abstract: OASL Produits

Synonymes: anticorps Oasl1, anticorps oasl9, anticorps 7530414C13Rik, anticorps OASLd, anticorps TRIP-14, anticorps TRIP14, anticorps p59 OASL, anticorps p59-OASL, anticorps p59OASL, anticorps 2'-5'-oligoadenylate synthetase-like, anticorps 2'-5' oligoadenylate synthetase-like 1, anticorps 2'-5'-oligoadenylate synthetase like, anticorps 2'-5'-oligoadenylate synthase-like protein, anticorps Oasl, anticorps Oasl1, anticorps OASL, anticorps LOC100356242, anticorps LOC100483471

Sujet: 2-prime,5-prime oligoadenylates (2-5As) bind to and activate RNase L, leading to degradation of RNA and inhibition of protein synthesis. 2-5As are produced by 2-5A synthetases (OASs), a highly-conserved family of interferon-induced enzymes. The predicted 514-amino acid human p59OASL (2-5A synthetases-like) protein shares a highly conserved N-terminal domain with other OASs. The C-terminal portion of p59OASL contains 2 ubiquitin-like domains. p59OASL is expressed in most tissues, with the highest levels in hematopoietic tissues, colon, and stomach.Synonyms: 59 kDa 2'-5'-oligoadenylate synthetase-like protein, TR-interacting protein 14, Thyroid receptor-interacting protein 14, p59 OASL

ID gène: 8638, 9606

UniProt: Q15646