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PARP12 anticorps (C-Term)

PARP12 Reactivité: Humain WB, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN358822
  • Antigène Tous les produits PARP12
    PARP12 (Poly (ADP-Ribose) Polymerase Family, Member 12 (PARP12))
    Épitope
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 18
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 17
    • 1
    Lapin
    Clonalité
    • 18
    Polyclonal
    Conjugué
    • 15
    • 1
    • 1
    • 1
    Cet anticorp PARP12 est non-conjugé
    Application
    • 11
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts to PARP12.
    Purification
    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
    Immunogène
    This PARP12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of mouse PARP12.
    Isotype
    Ig Fraction
  • Indications d'application
    ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène
    PARP12 (Poly (ADP-Ribose) Polymerase Family, Member 12 (PARP12))
    Autre désignation
    PARP12 (PARP12 Produits)
    Synonymes
    anticorps ARTD12, anticorps MST109, anticorps MSTP109, anticorps ZC3H1, anticorps ZC3HDC1, anticorps 9930021O16, anticorps AA409132, anticorps AA536654, anticorps PARP-12, anticorps Zc3hdc1, anticorps PARP12, anticorps zc3h1, anticorps mst109, anticorps mstp109, anticorps zc3hdc1, anticorps si:ch211-227d19.2, anticorps poly(ADP-ribose) polymerase family member 12, anticorps poly (ADP-ribose) polymerase family, member 12, anticorps poly(ADP-ribose) polymerase family member 12 L homeolog, anticorps poly (ADP-ribose) polymerase family, member 12a, anticorps poly [ADP-ribose] polymerase 12, anticorps PARP12, anticorps Parp12, anticorps parp12.L, anticorps parp12a, anticorps parp12, anticorps LOC100561568
    Sujet
    Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. Poly(ADP-ribose) polymerases (PARPs) now constitute a large family of 18 proteins, encoded by different genes and displaying a conserved catalytic domain in which PARP-1 (113 kDa), the founding member, and PARP-2 (62 kDa) are so far the sole enzymes whose catalytic activity has been shown to be immediately stimulated by DNA strand breaks. A large repertoire of sequences encoding novel PARPs now extends considerably the field of poly(ADP-ribosyl)ation reactions to various aspects of the cell biology including cell proliferation and cell death. Some of these new members interact with each other, share common partners and common subcellular localizations suggesting possible fine tuning in the regulation of this post-translational modification of proteins.Synonyms: PARP-12, Poly [ADP-ribose] polymerase 12, ZC3HDC1, Zinc finger CCCH domain-containing protein 1
    ID gène
    243771, 10090
    UniProt
    Q8BZ20
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