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Parkin anticorps (N-Term)

Cet anticorps anti-Parkin est un anticorps Lapin Polyclonal détectant Parkin dans WB et EIA. Adapté pour Drosophila melanogaster.
N° du produit ABIN359013

Aperçu rapide pour Parkin anticorps (N-Term) (ABIN359013)

Antigène

Parkin (PARK)

Reactivité

Drosophila melanogaster

Hôte

  • 1
Lapin

Clonalité

  • 1
Polyclonal

Conjugué

  • 1
Cet anticorp Parkin est non-conjugé

Application

Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Épitope

    • 1
    • 1
    N-Term

    Specificité

    This antibody reacts to Parkin.

    Purification

    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

    Immunogène

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of Drosophila Parkin.

    Isotype

    Ig Fraction
  • Indications d'application

    ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.25 mg/mL

    Buffer

    PBS with 0.09 % (W/V) sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-28 °C for longer.
  • Antigène

    Parkin (PARK)

    Autre désignation

    PARKIN / Park

    Sujet

    Parkin is thought to play a role in the ubiquitin/proteasome pathway for protein degradation. The amino terminus bears sequence homology to ubiquitin while functionally it acts as a RING-type ubiquitin protein ligase (E3) that coordinates the transfer of ubiquitin to substrate proteins, thus targeting them for degradation by the proteasome. Mutations in the human version of the protein are known to cause autosomal recessive juvenile parkinsonism.

    ID gène

    40336, 7227

    UniProt

    Q7KTX7
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