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STRADB anticorps (C-Term)

STRADB Reactivité: Humain WB, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN359240
  • Antigène Voir toutes STRADB Anticorps
    STRADB (STE20-Related Kinase Adaptor beta (STRADB))
    Épitope
    • 14
    • 8
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 28
    • 26
    • 3
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 40
    • 2
    • 1
    Lapin
    Clonalité
    • 41
    • 1
    Polyclonal
    Conjugué
    • 22
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp STRADB est non-conjugé
    Application
    • 32
    • 23
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts to ALS2CR2.
    Purification
    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
    Immunogène
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ALS2CR2.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product STRADB Anticorps primaire
  • Indications d'application
    ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène
    STRADB (STE20-Related Kinase Adaptor beta (STRADB))
    Autre désignation
    STRAD beta / ILPIP (STRADB Produits)
    Synonymes
    anticorps Als2cr2, anticorps RGD1559449, anticorps als2cr2, anticorps MGC82468, anticorps STRADB, anticorps ALS2CR2, anticorps AA792893, anticorps B830008M19, anticorps D1Ucla2, anticorps ILPIP, anticorps ILPIPA, anticorps PRO1038, anticorps Papk, anticorps Syradb, anticorps CALS-21, anticorps PAPK, anticorps STE20-related kinase adaptor beta, anticorps STE20-related kinase adaptor beta L homeolog, anticorps Stradb, anticorps STRADB, anticorps stradb.L
    Sujet
    ALS2CR2 potentiates the antiapoptotic activity of XIAP by enhancing XIAP-mediated activation of JNK1 (MAPK8) and other JNK family members, but not by modulating XIAP-mediated caspase inhibition. Expression of a catalytically inactive TAK1 (MAP3K7) mutant blocks the XIAP/ALS2CR2 activation of JNK1. In vivo coprecipitation experiments show that both ALS2CR2 and XIAP interact with TAK1 and TRAF6. It has been proposed that XIAP-mediated protection from apoptosis utilizes both a JNK1 activation pathway that involves ALS2CR2 and a caspase inhibition pathway that is independent of ALS2CR2.Synonyms: ALS2CR2, CALS-21, PRO1038, Pseudokinase ALS2CR2, STE20-related kinase adapter protein beta, STRADB
    ID gène
    55437, 9606
    UniProt
    Q9C0K7
    Pathways
    AMPK Signaling
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