PANK2 anticorps (Middle Region)

N° du produit ABIN359321

Détail du produit anti-PANK2 anticorps

Antigène: PANK2 (Pantothenate Kinase 2 (PANK2))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PANK2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to PANK2.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the central region of human PANK2.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur PANK2

Antigène: PANK2 (Pantothenate Kinase 2 (PANK2))

Autre désignation: PANK2 (PANK2 Produits)

Synonymes: anticorps ATPANK2, anticorps F10M6.180, anticorps F10M6_180, anticorps pantothenate kinase 2, anticorps PANK2, anticorps C20orf48, anticorps HARP, anticorps HSS, anticorps NBIA1, anticorps PKAN, anticorps 4933409I19Rik, anticorps AI642621, anticorps pantothenate kinase 2, anticorps pantothenate kinase 2, mitochondrial, anticorps ribonuclease A family member 11 (inactive), anticorps PANK2, anticorps Tsp_01576, anticorps LOC100539295, anticorps Pank2, anticorps RNASE11

Sujet: Pantothenate kinase is an essential regulatory enzyme in CoA biosynthesis, catalyzing the cytosolic phosphorylation of pantothenate (vitamin B5), N-pantothenoylcysteine, and pantetheine. CoA is the major acyl carrier, playing a central role in intermediary and fatty acid metabolism. In both yeast and fly, each with only 1 pantothenate kinase gene, the null mutant is inviable. Mutations in PANK2 are the cause of pantothenate kinase-associated neurodegeneration (PKAN), formerly known as Hallervorden-Spatz syndrome (HSS). PKAN is an autosomal recessive neurodegenerative disorder associated with iron accumulation in the brain. Mutations in PANK2 are the cause of hypoprebetalipoproteinemia, acanthocytosis, retinitis pigmentosa, and pallidal degeneration (HARP).Synonyms: C20orf48, Pantothenate kinase 2 mitochondrial, Pantothenic acid kinase 2

ID gène: 80025, 9606

UniProt: Q9BZ23

Pathways: Ribonucleoside Biosynthetic Process