DCXR anticorps (Middle Region)

N° du produit ABIN359606

L’anticorps Lapin Polyclonal anti-DCXR a été validé pour WB, IHC (p), FACS et EIA. Il convient pour détecter DCXR dans des échantillons de Humain et Souris.

Aperçu rapide pour DCXR anticorps (Middle Region) (ABIN359606)

Antigène: DCXR (Dicarbonyl/L-Xylulose Reductase (DCXR))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCXR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Détail du produit anti-DCXR anticorps

Épitope: Middle Region

Specificité: This antibody recognizes Human and Mouse DCXR. Other species not tested.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogène: KLH conjugated synthetic peptide between 79-106 amino acids from the Central region of Human DCXR.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000
Western blotting: 1/50 - 1/100
Immunohistochemistry on Paraffin Sections: 1/50-1/100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur DCXR

Antigène: DCXR (Dicarbonyl/L-Xylulose Reductase (DCXR))

Autre désignation: L-Xylulose Reductase

Sujet: DCXR is an enzyme that has both diacetyl reductase and L-xylulose reductase activities. Function: Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L- xylulose. Participates in the uronate cycle of glucose metabolism May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules. Cellular Location: Membrane, Peripheral membrane protein (By similarity). Note=Probably recruited to membranes via an interaction with phosphatidylinositol (By similarity). Tissue Location: Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis.Synonyms: Carbonyl reductase II, DCXR, Dicarbonyl/L-xylulose reductase, Kidney dicarbonyl reductase, P34H, Sperm surface protein P34H, XR

Poids moléculaire: 25913 Da (calculated)

ID gène: 51181, 9606

UniProt: Q7Z4W1

Pathways: Glycosaminoglycan Metabolic Process, Monocarboxylic Acid Catabolic Process