MATK anticorps (N-Term)

N° du produit ABIN359988

Détail du produit anti-MATK anticorps

Antigène: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MATK est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes MATK.

Réactivité croisée (Details): Species reactivity (tested):Human and Mouse.

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human MATK.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur MATK

Antigène: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Autre désignation: MATK (MATK Produits)

Synonymes: anticorps si:ch211-63j24.2, anticorps CHK, anticorps CTK, anticorps HHYLTK, anticorps HYL, anticorps HYLTK, anticorps Lsk, anticorps Ntk, anticorps Batk, anticorps megakaryocyte-associated tyrosine kinase, anticorps zinc finger RNA binding protein 2, anticorps matk, anticorps MATK, anticorps Matk, anticorps ZFR2

Sujet: MATK has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.Synonyms: CHK, CTK, HYL, HYLTK, Hematopoietic consensus tyrosine-lacking kinase, Megakaryocyte-associated tyrosine-protein kinase

ID gène: 4145, 9606

UniProt: P42679