PDX1 anticorps (N-Term)

N° du produit ABIN360026

Détail du produit anti-PDX1 anticorps

Antigène: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDX1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to PDX1.

Purification: Protein A column, followed by peptide affinity purification

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the ?-terminal region of human Ipf (Human N-term).

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur PDX1

Antigène: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Autre désignation: Insulin Promoter Factor 1 (PDX1 Produits)

Synonymes: anticorps GSF, anticorps IDX-1, anticorps IPF1, anticorps IUF1, anticorps MODY4, anticorps PDX-1, anticorps STF-1, anticorps ipf1, anticorps PDX1, anticorps IPF-1, anticorps Ipf1, anticorps Mody4, anticorps pdx-1, anticorps Idx1, anticorps Stf1, anticorps zgc:100874, anticorps XlHbox-8, anticorps xlhbox8, anticorps pancreatic and duodenal homeobox 1, anticorps pancreatic and duodenal homeobox 1 S homeolog, anticorps PDX1, anticorps pdx1, anticorps Pdx1, anticorps pdx1.S

Sujet: PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. This nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in the gene encoding PDX1 are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).Synonyms: GSF, Glucose-sensitive factor, IDX-1, IPF-1, IPF1, IUF-1, Insulin promoter factor 1, Insulin upstream factor 1, Islet/duodenum homeobox-1, PDX-1, PDX1, Pancreas/duodenum homeobox protein 1, STF-1, Somatostatin-transactivating factor 1

ID gène: 3651, 9606

UniProt: P52945

Pathways: Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location