DUSP1 anticorps (N-Term)

N° du produit ABIN360822

Cet anticorps anti-DUSP1 Polyclonal Lapin (ABIN360822) détecte spécifiquement DUSP1 dans WB et EIA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour DUSP1 anticorps (N-Term) (ABIN360822)

Antigène: DUSP1 (Dual Specificity Phosphatase 1 (DUSP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUSP1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-DUSP1 anticorps

Épitope: N-Term

Specificité: This antibody reacts to DUSP1.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human DUSP1.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur DUSP1

Antigène: DUSP1 (Dual Specificity Phosphatase 1 (DUSP1))

Autre désignation: DUSP1 / MKP1

Sujet: The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein hasintrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation.Synonyms: CL100, Dual specificity protein phosphatase 1, Dual specificity protein phosphatase hVH1, MAP kinase phosphatase 1, MKP-1, PTPN10, Protein-tyrosine phosphatase CL100, VH1

ID gène: 1843, 9606

UniProt: P28562