IGFBP2 anticorps
Aperçu rapide pour IGFBP2 anticorps (ABIN360900)
Antigène
Voir toutes IGFBP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody detects IGF-BP2. No cross activity to other IGFBPs.
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Purification
- Protein A/G affinity chromatography
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Immunogène
- Recombinant protein of IGF-BP2
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Isotype
- IgG2
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Indications d'application
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Reconstitution
- Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- IGFBP2 (Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2))
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Autre désignation
- IGFBP2
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Sujet
- IGFBP2 (insulin-like growth factor binding protein 2) is a member of the ISGBP family which bind various IGFs. IGFBP2 is overexpressed in a wide spectrum of other cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The overexpression of IGFBP2 also correlates with the aggressiveness of some tumors. IGFBP2 activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness.Synonyms: IBP-2, IBP2, IGF-binding protein 2, IGFBP-2, Insulin-like growth factor-binding protein 2
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ID gène
- 16008
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NCBI Accession
- NP_032368
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UniProt
- P47877
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Pathways
- Myometrial Relaxation and Contraction, Growth Factor Binding, Activated T Cell Proliferation
Antigène
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