IL1RL1 anticorps (Extracellular Domain)

N° du produit ABIN360904

Cet anticorps Rat Monoclonal détecte spécifiquement IL1RL1 dans WB. Il présente une réactivité envers Souris.

Aperçu rapide pour IL1RL1 anticorps (Extracellular Domain) (ABIN360904)

Antigène: IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL1RL1 est non-conjugé

Application: Western Blotting (WB)

Clone: 3F22

Détail du produit anti-IL1RL1 anticorps

Épitope: Extracellular Domain

Specificité: This antibody detects IL-1 R4.

Purification: Protein A/G Affinity Chromatography

Stérilité: 0.2 μm filtered

Immunogène: Purified Mouse Recombinant IL-1 R4 extracellular doamin

Isotype: IgG2

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Buffer: Lyophilized from a 0.2 μm filtered solution in PBS

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IL1RL1

Antigène: IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))

Autre désignation: IL1RL1 / ST2

Sujet: ST2 is a member of the Toll-Interleukin 1 receptor (TIR) superfamily, expressed by mast cells and TH2 helper cells, but not by TH1 effector cells. The majority of TIR superfamily members, which includes the Interleukin-1 receptor (IL-1R1), Toll-like receptors (TLRs) and the cytosolic adaptor proteins MyD88, TIRAP, Trif and TRAM, initiate innate immunity through the ultimate activation of the transcription factor NF-kappaB and are inducers of the inflammatory response. In contrast ST2, which itself is unable to activate NF-kappaB, has been identified as a negative regulator of IL-1R1 and TLR4 signaling by sequestering MyD88 and TIRAP, in line with its role as a crucial receptor in TH2-cell mediated responses.Synonyms: DER4, FIT-1, Homolog of mouse growth stimulation-expressed, Interleukin-1 receptor-like 1, MGC32623

ID gène: 17082

NCBI Accession: NP_001020773

UniProt: P14719